BONE GRAFTING
Bone grafting, or transplanting of bone tissue, is beneficial in fixing bones that are damaged from trauma or problem joints. It’s also useful for growing bone around an implanted device, such as a total knee replacement where there is bone loss or a fracture. A bone graft may fill an area where bone is absent or help provide structural stability.
The bone used in a bone graft can come from your body or a donor, or it can be entirely synthetic (bioartificial). It can provide a framework where new, living bone can grow if it’s accepted by the body. At KYERON we are a specialist in the se bioartifical bone grafts – produced from natural elements at state-of-art facilities in Europe.
Bone is a highly vascularised tissue that constantly undergoes remodelling as a result of the balance between the activities of the osteoclasts and the osteoblasts, which allows adaptation to mechanical stresses, maintenance of bone health, and repair of small injuries. The coupling between osteoclastic bone resorption and osteoblastic bone formation is needed for bone homeostasis. Because of the potential of bone to spontaneously regenerate, most small bone lesions, such as fractures, heal well with conventional therapy or surgery.
During bone repair, the osteogenic process, under the influence of bone-derived bioactive factors, commences after the inflammatory phase and is initiated by precursor cells from the periosteum adjacent to the fracture site. This generates hard callus by intramembranous bone formation.
An autologous bone graft or bone substitute is often required to assist in the healing of an extensive traumatic or postsurgical bone defect and of osseous congenital deformities.
The use of bioartificial bone grafts, like the bone graft substitutes KYERON can offer, may help to overcome the problems of donor site morbidity and size limitations.
Within the group of bioartifical bone grafts we can differentiate the main groups of calcium phosphates and calcium sulphates. The calcium phosphates are widely recognized for the excellent combination of high compression strength, resorption ability and rate, osteoconduction and osteointergration.
Our bioartifical bone grafts have great osteoconductive and osteointergration properties which guides the reparative growth of the native bone. The materials (natural elements) we use for the bone graft serves as the framework for the new bone growth that is propagated by the patient’s natural bone. Osteoblasts from the defected area that is being grafted utilize the grafting material as a scaffold. The osteoblasts use this framework to spread and create new bone.
Guiding new bone growth requires the use of a efficient, usable and affortable bone-graft that is excellent for osteoconduction and osteointergration.
HA/TCP GRANULES
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