SYNOZ ONE® shall be used for the relief of pain and stiffness of the knee joint and other synovial joints in patients with degenerative and traumatic changes to the synovial joint.

Our intra-articular injectables are minor medical interventions, often performed by a general practitioner. These treatments allow the patient to live without the limitations of pain. To stay mobile and enjoy everyday activities. And to postpone the (costly) replacement of a joint, such as the knee.

Crosslinked

SYNOZ ONE® is a highly effective long lasting intra-articular injection.

Mono injection

A single injection of SYNOZ ONE® for long-lasting pain relief.

Ultra-high viscosity

SYNOZ ONE® has the ultimate viscous capacity; the highest possible shock absorption and friction reduction.

60 mg HA per syringe

SYNOZ ONE® provide the ideal amount of HA in a small volume.

Why two different injectables?

Our SYNOZ-solutions have vital qualities in common. They are both manufactured in state of the art European facilities, according to the highest quality standards. They have ultra-high sterility, are water soluble and from bio fermentative origin (no chemicals or animal proteins). They also have essential differences. Their specific product features ensure one of them is the perfect fit for the individual patient’s condition:

SYNOZ Sodium hyaluronate is manufactured by fermentation of Streptococcus equi and rigorously purified

Multiple injections or just One

The SYNOZ-injections are administered once a week, up to fi ve injections in total. This weekly treatment allows both doctor and patient to monitor the effects and progress. With SYNOZ ONE®, only one injection is administered; a very effi cient solution in certain cases, and advantageous for both physician and patient. Both treatments are suitable for all synovial joints. The doctor or specialist can determine which procedure best meets the patient’s needs.

Kyeron Quality Guarantee

THE STERILIZATION METHOD IS AN ESSENTIAL PART OF SAFETY
Terminal steam sterilization of SYNOZ ONE® guarantees inner and outer sterility of the syringe. This
special sterilization method guarantees a sterility grade of the syringe which is 1.000 times higher
compared to conventional methods.

LESS RISKS FOR POSSIBLE CONTAMINATION AND FOR SEVERE ACUTE INFLAMMATORY REACTIONS
Safer to use non‐animal, but only bio‐fermented SYNOZ ONE®.

Patented cross-linked molecules

Viscosity is key when treating a synovial joint for pain relieve. SYNOZ ONE® has the ultimate viscous capacity; the highest possible shock absorption and friction reduction. To reach that level of viscosity, we developed a patented cross-linked molecular composition. A dense hyaluronic acid network, interconnecting the individual hyaluronic acid molecules. The stabilization, achieved by a patented process, slows down the enzymatic degradation of the hyaluronic acid. The result is a superb, long-lasting cushion that protects the joint.

 

Cleanest in class

Kyeron is dedicated to creating the cleanest possible products. The first medical solutions we developed, were bio-materials for open surgery. The risks of infection, allergy and inflammation peak during such procedures. Therefore, we have taken unprecedented sterility and safety measures, from day one.

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